Central to this research is the creation of a custom bioreactor called the “Tissue Orb,” designed to mimic the natural blood flow of human tissues. This bioreactor features an artificial blood vessel and an automated system for media exchange, enabling the self-assembly process to occur efficiently in space’s weightless environment. Early results indicate that liver tissues developed in microgravity show better differentiation and functionality than those grown under standard Earth conditions, a promising step toward creating viable liver tissue implants. Future Applications and Cryopreservation Innovations In addition to tissue engineering, the research team is developing advanced cryopreservation techniques, such as isochoric supercooling, to safely transport tissues back to Earth. This method allows tissues to be stored below freezing without sustaining damage, potentially extending the shelf life of engineered tissues for future biomedical applications, including drug testing, disease modelling, and therapeutic implants.